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Table 3 Test performance of HPV DNA test (N = 504) and 5-type-mRNA test (N = 536) in solved cases

From: 5-type HPV mRNA versus 14-type HPV DNA test: test performance, over-diagnosis and overtreatment in triage of women with minor cervical lesions

Triage status

CIN2+

CIN1-

Total

HPV DNA positive

38

73

111a

HPV DNA negative

0

393

393

Total

38

466

504

Triage status

CIN2+

CIN1-

Total

HPV mRNA positive

30

47

77

HPV mRNA negative

8

451

459

Total

38

498

536

  1. CIN2+ CIN2, CIN3, ACIS, and cervical cancer
  2. CIN1- Normal and CIN1
  3. aOf the 111 women with a positive HPV DNA test, six women had normal cytology and a negative HPV DNA test at second follow-up and returned to screening at 3-year interval