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Table 2 Most severe histology from biopsy/cone specimen by HPV test

From: 5-type HPV mRNA versus 14-type HPV DNA test: test performance, over-diagnosis and overtreatment in triage of women with minor cervical lesions

Histology HPV DNA 5-type-mRNA
N = 105 % (95 % CI) N = 77 % (95 % CI)
Normal/CIN1 67 63.8 (54.6–73.0) 47 61.0 (50.1–71.9)
CIN2 23 21.9 (14.0–29.8) 15 19.5 (10.7–28.3)
CIN3+ 15 14.3 (7.6–21.0) 15 19.5 (10.7–28.3)
  1. CIN cervical intraepitelial neoplasi
  2. HPV DNA HPV DNA test (Cobas 4800)
  3. 5-type-mRNA HPV mRNA test (PreTect HPV-Proofer)